ABSTRACT
OBJECTIVE: To explore the value of CT quantitative detection of pulmonary lesions in diagnosis and treatment of COVID-19. METHODS: A total of 14 patients with COVID-19 who were treated in Quzhou People's Hospital from Jan 2020 to Apr 2020 were enrolled in the study and received chest scanning examination at the admission, progression stage of disease, recovery stage and absorption stage, the CT thin-slice scan data were imported into Toshiba Vitrea FX workstation, and the total volume, maximum diameter, maximum density and average density of pulmonary lesions were measured by using the quantitative detection function of lung lesions, and the distribution and scope of lesions were displayed in three dimensions by means of visualization technology. RESULTS: The results of the four times of CT examination showed that there were between-group significant differences in the volume of lesions, maximum density and maximum diameter during the different time periods. The volume of lesions, maximum density and maximum diameter of the patients who received the second CT examination were significantly higher than those of the patients who received other three times of CT examination;the volume of lesions, maximum density and maximum diameter of the patients who received the fourth CT examination were significantly lower than those of the patients who received other three times of CT examination(P < 0.05). CONCLUSION: The CT quantitative detection technology of lung lesions can quantify the information of lung lesions such as the total volume, maximum diameter, density, distribution and scope, continuously observe the course of disease and indicate the stage of lesions for clinicians so as to adjust the treatment program in a timely manner.